Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pseC (O25130) - Overview - Molecular Target Synopsis

Protein


pseC, UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
Enzyme Classification 2.6.1.92
UniProt O25130

Also Known as PSEC_HELPY, pseC

Catalyzes the second step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Uses UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose as substrate producing UDP-4-amino-4,6-dideoxy-beta-L-AltNAc.

2FN6
HELICOBACTER PYLORI PSEC, AMINOTRANSFERASE INVOLVED IN THE BIOSYNTHESIS OF PSEUDOAMINIC ACID
RCSB/PDB
Inspect Structure
See all 3D Structures for pseC

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
375O25130-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project pseC has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pseC there are:
3 structures (6 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis