Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

CPK2 (O15865) - Overview - Molecular Target Synopsis

Protein


CPK2, Calcium-dependent protein kinase 2
Enzyme Classification 2.7.11.1
UniProt O15865

Also Known as CDPK2_PLAFK, CPK2, CDPK2

Calcium-dependent kinase that may play a role in mosquito transmission of P.falciparum.

4MVF
CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM CDPK2 COMPLEXED WITH INHIBITOR STAUROSPORINE
RCSB/PDB
Inspect Structure
See all 3D Structures for CPK2

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
513O15865-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project CPK2 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For CPK2 there are:
2 structures (3 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


CPK2 has been screened with compounds ( bioactivities). (see details)