Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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Germline Genetics

ABCC3 (O15438) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TGK_A 36.32 3.0E-12 DTP
ABC transporter (100%) (view alignment) lmrA (Q9CHL8) - 1MV5_B 35.81 7.0E-18 ADP
ABC transporter (100%) (view alignment) Cftr (P26361) - 3SI7_C 36.49 2.0E-37 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFJ_A 36.32 3.0E-12 DCP
ABC transporter (100%) (view alignment) (Q9WYC4) - 4Q7L_B 38.4 4.0E-22 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 1Q3H_A 36.97 9.0E-11 ANP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFC_A 36.32 3.0E-12 GTP
ABC transporter (100%) (view alignment) (A0A0E1SLC7) - 5EUM_B 37.29 2.0E-21 MLZ
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Z_D 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2BBO_A 36.54 9.0E-38 ATP
ABC transporter (100%) (view alignment) lmrA (Q9CHL8) - 1MV5_C 35.81 7.0E-18 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 3SI7_B 36.49 2.0E-37 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2BBS_B 38.58 8.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFB_A 36.32 3.0E-12 MGP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1XF9_A 36.49 4.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1XFA_A 36.49 6.0E-11 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2BBS_A 38.58 8.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 1XMI_A 37.5 5.0E-12 ATP
ABC transporter (100%) (view alignment) lmrA (Q9CHL8) - 1MV5_A 35.81 7.0E-18 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0W_C 36.97 9.0E-11 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0X_C 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2BBT_B 38.58 7.0E-12 ATP
ABC transporter (100%) (view alignment) (Q9WYC4) - 4Q7L_C 38.4 4.0E-22 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0W_D 36.97 9.0E-11 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0W_A 36.97 9.0E-11 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Z_A 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2PZE_A 36.32 3.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 1XMI_B 37.5 5.0E-12 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 3SI7_A 36.49 2.0E-37 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 4WZ6_A 38.58 8.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFD_A 36.32 3.0E-12 CTP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Y_D 36.97 9.0E-11 ADP
ABC transporter (100%) (view alignment) CFTR (P13569) - 1XMJ_A 36.06 1.0E-35 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFI_A 36.32 3.0E-12 DGT
ABC transporter (100%) (view alignment) Cftr (P26361) - 1XF9_D 36.49 4.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Z_C 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2PZF_A 35.87 1.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1XF9_B 36.49 4.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Y_C 36.97 9.0E-11 ADP
ABC transporter (100%) (view alignment) malK (P68187), CFTR (P13569) - 3GD7_C 36.16 3.0E-41 B44
ABC transporter (100%) (view alignment) ABCC1 (P33527) - 2CBZ_A 66.67 7.0E-12 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1XFA_B 36.49 6.0E-11 ATP
ABC transporter (100%) (view alignment) (Q9WYC4) - 4Q7M_B 38.4 4.0E-22 -
ABC transporter (100%) (view alignment) lmrA (Q9CHL8) - 1MV5_D 35.81 7.0E-18 ADP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Z_B 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2BBT_A 38.58 7.0E-12 ATP
ABC transporter (100%) (view alignment) ABCC6 (O95255) - 6BZR_A 56.8 8.0E-11 ADP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFF_A 36.32 3.0E-12 UTP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2PZG_B 35.98 4.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 1XMI_C 37.5 5.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TF7_A 36.32 3.0E-12 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0X_D 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) ABCC6 (O95255) - 6BZS_A 59.19 3.0E-12 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R10_B 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1Q3H_D 36.97 9.0E-11 ANP
ABC transporter (100%) (view alignment) CFTR (P13569) - 1XMI_E 37.5 5.0E-12 ATP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TF8_A 36.32 3.0E-12 TTP
ABC transporter (100%) (view alignment) CFTR (P13569) - 2PZG_A 35.98 4.0E-12 ATP
ABC transporter (100%) (view alignment) (A0A0E1SLC7) - 5EUM_A 37.29 2.0E-21 MLZ
ABC transporter (100%) (view alignment) CFTR (P13569) - 2PZE_B 36.32 3.0E-12 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0X_B 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1Q3H_C 36.97 9.0E-11 ANP
ABC transporter (100%) (view alignment) ABCC6 (O95255) - 6BZR_B 56.8 8.0E-11 ADP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFA_A 36.32 3.0E-12 DUT
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0W_B 36.97 9.0E-11 -
ABC transporter (100%) (view alignment) CFTR (P13569) - 1XMI_D 37.5 5.0E-12 ATP
ABC transporter (100%) (view alignment) malK (P68187), CFTR (P13569) - 3GD7_B 36.16 3.0E-41 B44
ABC transporter (100%) (view alignment) Cftr (P26361) - 1XF9_C 36.49 4.0E-11 ATP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0X_A 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) ABCC1 (P33527) - 4C3Z_A 62.45 1.0E-11 -
ABC transporter (100%) (view alignment) (Q9WYC4) - 4Q7L_A 38.4 4.0E-22 -
ABC transporter (100%) (view alignment) malK (P68187), CFTR (P13569) - 3GD7_D 36.16 3.0E-41 B44
ABC transporter transmembrane region (100%), ABC transporter (100%) (view alignment) ABCC1 (Q8HXQ5) - 6BHU_A 57.12 0 CLR ATP
ABC transporter transmembrane region (100%), ABC transporter (100%) (view alignment) ABCC1 (Q8HXQ5) - 5UJA_A 57.54 0 LTX
ABC transporter (100%) (view alignment) CFTR (P13569) - 2PZF_B 35.87 1.0E-11 ATP
ABC transporter transmembrane region (100%), ABC transporter (100%) (view alignment) ABCC1 (Q8HXQ5) - 5UJ9_A 57.54 0 -
ABC transporter (100%) (view alignment) Cftr (P26361) - 3SI7_D 36.49 2.0E-37 ATP
ABC transporter (100%) (view alignment) malK (P68187), CFTR (P13569) - 3GD7_A 36.16 3.0E-41 B44
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Y_B 36.97 9.0E-11 ADP
ABC transporter (100%) (view alignment) CFTR (P13569) - 5TFG_A 36.32 3.0E-12 M5T
ABC transporter (100%) (view alignment) Cftr (P26361) - 1Q3H_B 36.97 9.0E-11 ANP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R0Y_A 36.97 9.0E-11 ADP
ABC transporter (100%) (view alignment) Cftr (P26361) - 1R10_A 36.97 9.0E-11 ATP
ABC transporter (100%) (view alignment) - 5IDV_A 36.97 3.0E-24 -