Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Interaction Network
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Gene Copy Number Variation
RNAi
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Germline Genetics

ALOX15B (O15296) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3O8Y_B 42 0 2.389Å - 2011-01-19
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3O8Y_A 42 0 2.389Å - 2011-01-19
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_B 38.37 4.0E-98 1.89Å OYP 2012-04-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V99_B 42.14 0 2.25Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V92_A 42 0 2.74Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V99_A 42.14 0 2.25Å ACD 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15B (O15296) - HUMAN 4NRE_A 100 0 2.63Å C8E 2014-02-12
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V98_B 42.14 0 2.07Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15 (P12530) - RABBIT 2P0M_A 36.99 8.0E-113 2.4Å - 2007-10-09
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V92_B 42 0 2.74Å - 2012-05-02
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15 (P12530) - RABBIT 1LOX_A 36.99 1.0E-112 2.4Å RS7 1998-11-04
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_A 38.37 4.0E-98 1.89Å OYP 2012-04-18
Lipoxygenase (100%) (view alignment) ALOX12 (P18054) - 3D3L_B 38.76 6.0E-97 2.6Å - 2008-09-09
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX5 (P09917) - HUMAN 3V98_A 42.14 0 2.07Å - 2012-05-02
Lipoxygenase (100%) (view alignment) ALOX12 (P18054) - 3D3L_A 38.76 6.0E-97 2.6Å - 2008-09-09
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_C 38.37 4.0E-98 1.89Å OYP 2012-04-18
Lipoxygenase (100%) (view alignment) ALOX15 (P16469) - PIGS,SWINE,WILD BOAR 3RDE_D 38.37 4.0E-98 1.89Å OYP 2012-04-18
PLAT/LH2 domain (100%), Lipoxygenase (100%) (view alignment) ALOX15 (P12530) - RABBIT 2P0M_B 36.99 8.0E-113 2.4Å RS7 2007-10-09