Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLC17A2 (O00624) - Overview - Molecular Target Synopsis

Protein


SLC17A2, Sodium-dependent phosphate transport protein 3
UniProt O00624

Also Known as NPT3_HUMAN, SLC17A2, NPT3

May be involved in actively transporting phosphate into cells via Na(+) cotransport.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: SLC17A2 is active in the following subcellular-locations: membrane.
GO terms: SLC17A2 is active in the following subcellular-locations: integral component of membrane, integral component of plasma membrane, lysosome, membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLC17A2 has gain in 3 cell-lines, loss in 1 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: MCF7, HL_60, SK_OV_3

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)


Screening and Chemistry


SLC17A2 has been screened with compounds ( bioactivities). (see details)