SLC17A3 (O00476) - Overview - Molecular Target Synopsis
SLC17A3, Sodium-dependent phosphate transport protein 4
Also Known as NPT4_HUMAN, SLC17A3, NPT4
Isoform 2: voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
|420||ENSG00000124564||ENST00000360657, ENST00000361703||ENSP00000353873, ENSP00000355307||O00476-1|
UniProt: SLC17A3 is active in the following subcellular-locations: cell membrane, endoplasmic reticulum membrane.
GO terms: SLC17A3 is active in the following subcellular-locations: apical plasma membrane, brush border membrane, cytoplasm, endoplasmic reticulum membrane, integral component of membrane, integral component of plasma membrane, lysosome, perinuclear region of cytoplasm, plasma membrane.