Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLCO1B7 (G3V0H7) - Overview - Molecular Target Synopsis

Protein


SLCO1B7, Putative solute carrier organic anion transporter family member 1B7
UniProt G3V0H7

Also Known as SO1B7_HUMAN, SLCO1B7, LST3, LST3TM12

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
640ENSG00000205754ENST00000421593ENSP00000394168G3V0H7-1
99ENSG00000205754ENST00000545916ENSP00000439857

Sub-cellular localization


UniProt: SLCO1B7 is active in the following subcellular-locations: cell membrane.
GO terms: SLCO1B7 is active in the following subcellular-locations: integral component of plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLCO1B7 has gain in 12 cell-lines, loss in 5 cell-lines and no signal in 988 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H209, Hs 746T, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)


Screening and Chemistry


SLCO1B7 has been screened with compounds ( bioactivities). (see details)