Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

PF12 (C6KSX0) - Overview - Molecular Target Synopsis

Protein


PF12, Merozoite surface protein P12
UniProt C6KSX0

Also Known as PF12_PLAF7, PF12

Heterodimer; heterodimerizes with PF41. May form an antiparallel heterodimer with PF41.

2YMO
CRYSTAL STRUCTURE OF PF12 TANDEM 6-CYS DOMAINS FROM PLASMODIUM FALCIPARUM
RCSB/PDB
Inspect Structure
See all 3D Structures for PF12

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
347C6KSX0-1

Sub-cellular localization


UniProt: PF12 is active in the following subcellular-locations: cell membrane, cell surface.
GO terms: PF12 is active in the following subcellular-locations: anchored component of plasma membrane, apical part of cell, cell surface, symbiont-containing vacuolar space.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project PF12 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For PF12 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis