Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

FABP5P3 (A8MUU1) - Overview - Molecular Target Synopsis

Protein


FABP5P3, Putative fatty acid-binding protein 5-like protein 3
UniProt A8MUU1

Also Known as FB5L3_HUMAN, FABP5P3, FABP5L3

High specificity for fatty acids.

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
101A8MUU1-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project FABP5P3 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)

3D Structures


At greater than 90% identity similarity to FABP5P3 there are:
8 structures (20 chains) solved
6 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


FABP5P3 has been screened with compounds ( bioactivities). (see details)