MFSD2B (A6NFX1) - Overview - Molecular Target Synopsis
MFSD2B, Major facilitator superfamily domain-containing protein 2B
Also Known as MFS2B_HUMAN, MFSD2B
Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets (PubMed:29045386). Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Does not transport lysophosphatidylcholine (LPC).
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: MFSD2B is active in the following subcellular-locations: cell membrane.
GO terms: MFSD2B is active in the following subcellular-locations: integral component of plasma membrane.