, DNA-binding protein Bv3F
Also Known as
A DNA-binding protein implicated in transcriptional repression and chromosome organization and compaction. Binds in the minor groove of AT-rich DNA (PubMed:21673140). Binds nucleation sites in AT-rich DNA and bridges them, forming higher-order nucleoprotein complexes and condensing the chromosome. As many horizontally transferred genes are AT-rich, it plays a central role in silencing foreign genes (By similarity). Homodimer that oligomerizes on DNA into higher-order complexes that form bridges between disparate regions of DNA compacting it (By similarity).