Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

pth (A0R3D3) - Overview - Molecular Target Synopsis

Protein


pth, Peptidyl-tRNA hydrolase
Enzyme Classification 3.1.1.29
UniProt A0R3D3

Also Known as PTH_MYCS2, pth

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Monomer.

2NAF
SOLUTION STRUCTURE OF PEPTIDYL-TRNA HYDROLASE FROM MYCOBACTERIUM SMEGMATIS
RCSB/PDB
Inspect Structure
See all 3D Structures for pth

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
191A0R3D3-1

Sub-cellular localization


UniProt: pth is active in the following subcellular-locations: cytoplasm.
GO terms: pth is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project pth has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For pth there are:
5 structures (5 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis