Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

TLDC2 (A0PJX2) - Overview - Molecular Target Synopsis


TLDC2, TLD domain-containing protein 2
UniProt A0PJX2

Also Known as TLDC2_HUMAN, TLDC2

Isoforms / Transcripts (Protein Coding)

Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
215ENSG00000101342ENST00000602922, ENST00000217320ENSP00000473323, ENSP00000217320A0PJX2-1

Gene Copy Number Variation

In COSMIC - Cell Lines Project TLDC2 has gain in 7 cell-lines, loss in 1 cell-lines and no signal in 997 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: COLO 205, COLO 206F, SNU-719

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)

3D Structures

At greater than 50% identity similarity to TLDC2 there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand

(see details)
Molecular Target 3D Synopsis