Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

rpsH (A0A0M9AFS9) - Overview - Molecular Target Synopsis

Protein


rpsH, 30S ribosomal protein S8
UniProt A0A0M9AFS9

Also Known as RS8_THEAQ, rpsH

One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit. Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

5LMN
STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1A)
RCSB/PDB
Inspect Structure
See all 3D Structures for rpsH

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization


GO terms: rpsH is active in the following subcellular-locations: ribosome.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpsH has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpsH there are:
111 structures (111 chains) solved
5 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis