Disease Synopsis
Overview
Drugs and Clinical Candidates
Clinical Trials (visual)
Clinical Trials (text)
Cell Line Models
Chemistry

Skin Cancer - Overview - Disease Synopsis

Drugs & Clinical Candidates


20 drugs have received FDA approval for Skin Cancer . Aldesleukin, Bexarotene, Binimetinib, Cemiplimab-rwlc, Cobimetinib, Dabrafenib, Dacarbazine, Encorafenib, Fluorouracil, Imiquimod, Ipilimumab, Nivolumab, PEGINTERFERON ALFA-2B, Pembrolizumab, Recombinant Interferon Alfa-2b, Sonidegib, Talimogene Laherparepvec, Trametinib, Vemurafenib and Vismodegib
313 drugs have a clinical trial registered for Skin Cancer.

Sources: cancer.gov and clinicaltrials.gov
(see details)

Clinical Trials


There are 1953 clinical trials for Skin Cancer,
1105 of which have one or more drug interventions,
848 with no drug intervention.

Sources: cancer.gov and clinicaltrials.gov
(see details)

Cell Line Models


There are 2237 Cell Line Models for Skin Cancer.

Source: COSMIC
(see details)

Chemistry


There are 7881 Compounds which have been tested in Skin Cancer , 5439 <= 500nM potency.

Source: ChEMBL
(see details)

Mappings


Please note the mappings below are based on an imperfect algorithm. If you notice any anomalies please report them to us.

The following terms have been mapped from clinicaltrials.gov mesh condition terms to Skin Cancer:
Carcinoma, Basal Cell
Carcinoma, Skin Appendage
Melanoma
Melanoma, Experimental
Neoplasms, Adnexal and Skin Appendage
Neoplasms, Basal Cell
Nevi and Melanomas
Skin Neoplasms

The following terms have been mapped from cancer.gov to Skin Cancer:
Cutaneous squamous cell carcinoma (a type of skin cancer) that is locally advanced or has metastasized (spread to other parts of the body). It is used in patients whose cancer cannot be cured by surgery or radiation therapy
Basal cell carcinoma (a type of skin cancer). It is used in adults whose disease has metastasized (spread to other parts of the body). It is also used in adults with locally advanced disease that has recurred (come back) after surgery or who cannot be treated with surgery or radiation
Basal cell carcinoma that is locally advanced. It is used in patients whose disease has recurred (come back) after surgery or radiation therapy or who cannot be treated with surgery or radiation therapy
Basal cell carcinoma that is superficial
Basal cell carcinoma that is superficial and cannot be removed by surgery. This use is approved for the Efudex brand of topical fluorouracil
In patients who have had surgery to remove melanoma that has spread to the lymph nodes or has metastasized
Melanoma in the skin and lymph nodes that cannot be removed by surgery. It is used as local treatment in patients whose disease has recurred (come back) after being treated with surgery
Melanoma that cannot be removed by surgery or has metastasized (spread to other parts of the body)
Melanoma that cannot be removed by surgery or has metastasized (spread to other parts of the body). It is used in patients whose cancer has a certain mutation in the BRAF gene
Melanoma that cannot be removed by surgery or has metastasized (spread to other parts of the body). It is used in patients whose disease has a certain mutation in the BRAF gene
Melanoma that has metastasized (spread to other parts of the body)
Melanoma. It is used in:Patients whose cancer cannot be removed by surgery or has metastasized (spread to other parts of the body) or
Melanoma. It is used as adjuvant therapy in adults who have had surgery and have a high risk of recurrent cancer
Melanoma. It is used as adjuvant therapy in patients who have had surgery to remove cancer that has spread to the lymph nodes. This use is approved for the Sylatron brand of peginterferon alfa-2b
Melanoma. It is used:In patients whose disease cannot be removed by surgery or has metastasized. It is sometimes used with ipilimumab
Melanoma. It is used:With dabrafenib in patients who have had surgery to remove cancer that has spread to the lymph nodes
Melanoma. It is used:With trametinib in patients who have had surgery to remove cancer that has spread to the lymph nodes
Melanoma.It is used as adjuvant therapy in patients with melanoma in the skin and lymph nodes who have already had surgery
Skin problems caused by cutaneous T-cell lymphoma that have not gotten better with other treatment