Disease Synopsis
Overview
Drugs and Clinical Candidates
Clinical Trials (visual)
Clinical Trials (text)
Cell Line Models
Chemistry

Kidney Cancer - Overview - Disease Synopsis

Drugs & Clinical Candidates


18 drugs have received FDA approval for Kidney Cancer . Aldesleukin, Amifostine, Axitinib, Bevacizumab, Cabozantinib-S-Malate, Dactinomycin, Doxorubicin Hydrochloride, Everolimus, Glucarpidase, Ipilimumab, Lenvatinib Mesylate, Nivolumab, Pazopanib Hydrochloride, Sodium, Sorafenib Tosylate, Sunitinib Malate, Temsirolimus and Vincristine Sulfate
247 drugs have a clinical trial registered for Kidney Cancer.

Sources: cancer.gov and clinicaltrials.gov
(see details)

Clinical Trials


There are 1021 clinical trials for Kidney Cancer,
745 of which have one or more drug interventions,
276 with no drug intervention.

Sources: cancer.gov and clinicaltrials.gov
(see details)

Cell Line Models


There are 224 Cell Line Models for Kidney Cancer.

Source: COSMIC
(see details)

Chemistry


There are 2896 Compounds which have been tested in Kidney Cancer , 1984 <= 500nM potency.

Source: ChEMBL
(see details)

Mappings


Please note the mappings below are based on an imperfect algorithm. If you notice any anomalies please report them to us.

The following terms have been mapped from clinicaltrials.gov mesh condition terms to Kidney Cancer:
Adrenal Cortex Neoplasms
Adrenal Gland Neoplasms
Carcinoma, Renal Cell
Kidney Neoplasms
Wilms Tumor

The following terms have been mapped from cancer.gov to Kidney Cancer:
As adjuvant therapy in adults who have had a nephrectomy (surgery to remove the kidney) and have a high risk that the cancer will recur (come back)
Hepatic veno-occlusive disease (also known as sinusoidal obstruction syndrome) in adults and children who also have kidney or lung problems after receiving a stem cell transplant
Renal (kidney) toxicity. It is used to reduce the nephrotoxic effects caused by repeated treatment with cisplatin for advanced ovarian cancer
Renal cell carcinoma (a type of kidney cancer) that has metastasized
Renal cell carcinoma (a type of kidney cancer) that is advanced
Renal cell carcinoma (a type of kidney cancer) that is advanced, in adults who have not gotten better after treatment with sunitinib or sorafenib
Renal cell carcinoma (a type of kidney cancer) that is advanced. It is used with nivolumab in some patients with renal cell carcinoma that has not been treated
Renal cell carcinoma (a type of kidney cancer) that is advanced. It is used in patients whose disease has not gotten better with other chemotherapy
Renal cell carcinoma (a type of kidney cancer) that is advanced. It is used with everolimus in patients who have already received angiogenesis inhibitor therapy
Renal cell carcinoma (a type of kidney cancer) that is advanced. It is used:In patients who have already received angiogenesis inhibitor therapy
Renal cell carcinoma (a type of kidney cancer) that is advanced. This use is approved for the Cabometyx brand of cabozantinib-s-malate
Renal cell carcinoma (a type of kidney cancer). It is used:In patients with advanced disease
Toxic blood levels of the anticancer drug methotrexate. Glucarpidase is used to remove methotrexate from the body in patients whose kidneys are not working as they should
Wilms tumor
With ipilimumab in some patients with renal cell carcinoma that has not been treated