Compound Synopsis
Compound Overview
Bioactivity Data Summary
Protein Affinity Profile
Cellline Sensitivity Profile

551660 - Overview - Compound Synopsis

Synonyms
CAPRELSACaprelsa
GNF-PF-2188GNF-Pf-2188
VANDETANIBVandetanib
ZD-64ZD-6474
ZD6ZD6474
Zactima
Molecular Formula
C22H24BrFN4O2
InChI
InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)
Smiles
COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1
Cross References
UniChem263028
canSAR551660
PDBe (Protein Data Bank Europe)ZD6
ChEMBLCHEMBL24828
BindingDB21
BindingDB4655
BindingDB31098
BindingDB50340915
Commercially Available
Yes
Protein Targets


MOLECULAR_WEIGHT ALOGP HBOND_DONORS HBOND_ACCEPTORS ATOMS CONTAINS_TOXICOPHORE
Properties 474.1066663285.00421654No


Compounds with the same scaffold


Image of compound ID: 551660
Murko Scaffold Family: 33 compoundsClick here to open a new canSAR search with these compounds

Maximum number shown here is 12





Compound Lineages


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