Compound Synopsis
Compound Overview
Bioactivity Data Summary
Protein Affinity Profile
Cellline Sensitivity Profile

1857 - Overview - Compound Synopsis

Synonyms
BAXBAY 43-9006
BAY-43-9006Nexavar
SORAFENIBSorafenib
Molecular Formula
C21H16ClF3N4O3
InChI
InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
Smiles
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1
Cross References
UniChem235132
canSAR1857
PDBe (Protein Data Bank Europe)BAX
ChEMBLCHEMBL1336
BindingDB16673
Commercially Available
Yes
Protein Targets


MOLECULAR_WEIGHT ALOGP HBOND_DONORS HBOND_ACCEPTORS ATOMS CONTAINS_TOXICOPHORE
Properties 464.0863027125.54973748Yes


Compounds with the same scaffold


Image of compound ID: 1857
Murko Scaffold Family: 360 compoundsClick here to open a new canSAR search with these compounds

Maximum number shown here is 12





Compound Lineages


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