Cell Line Synopsis
Cell Line Overview
Mutations
Copy Number Variation
Gene Expression
RNAi
Compound Sensitivity Profile
Similar Cell Lines

MCF-7 - Overview - Cell Line Synopsis

		

Cell Line Information


Name: MCF-7

Tissue: breast

Disease: adenocarcinoma, cancer, carcinoma



Gene Mutations


885 mutations were reported in COSMIC - Cell Lines Project
303 mutations were reported in COSMIC

(see details)



Copy Number Variation


COSMIC - Cell Lines Project reported the following signals for MCF-7.

153 Genes with gain
242 Genes with loss
57226 Genes with no signal

(see details)



Gene Expression


There are 1 source(s) of expression data for MCF-7.

In NCI - NCI 60 Reference:

Genes with the highest expression levels include EEF1A1, RPLP1, RPL41, RPS23, RPS2, EEF1AL7, LOC645715, RPS17, COX6C, RPS10.

Genes with the lowest expression levels include SSTR4, WNT1, CCDC3, LOC100292688, OR14J1, LOC653160, KRTAP9-4, IRF6, HBQ1, GALR3.

(see details)



RNAi


There are 1 source/s of RNAI data for MCF-7:

Broad Institute - Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(see details)