Cell Line Synopsis
Cell Line Overview
Mutations
Copy Number Variation
Gene Expression
RNAi
Compound Sensitivity Profile
Similar Cell Lines

HCT-116 - Overview - Cell Line Synopsis

		

Cell Line Information


Name: HCT-116

Tissue: colon, colorectal, large_intestine

Disease: adenocarcinoma, cancer, carcinoma



Gene Mutations


5293 mutations were reported in COSMIC - Cell Lines Project
1215 mutations were reported in COSMIC

(see details)



Copy Number Variation


COSMIC - Cell Lines Project reported the following signals for HCT-116.

0 Genes with gain
342 Genes with loss
57293 Genes with no signal

(see details)



Gene Expression


There are 1 source(s) of expression data for HCT-116.

In NCI - NCI 60 Reference:

Genes with the highest expression levels include EEF1A1, RPL41, RPS23, UNC5B, RPLP1, DCAF6, RPS2, HNRNPM, RPL23A, PPIA.

Genes with the lowest expression levels include GCGR, KRT75, SSTR4, RAMP3, KRTAP9-4, WNT1, TAAR2, HBQ1, PSMB8, GALR3.

(see details)



RNAi


There are 2 source/s of RNAI data for HCT-116:

Broad Institute - Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

Science - Cancer proliferation gene discovery through functional genomics

(see details)