3D Structure Inspector
Structure Overview
Ligand Interactions

5HE7 - Overview - 3D Structure Inspector

Atoms
Solvent
Spheres
Surface
Colour
Opacity
Texture
Background

LeftMouse Rotate
Shift+Left Scale
Ctrl+Left Translate
Click Select
+,− Clipping
r Reset view

AstexViewer™ Copyright (C) 1999-2007 Astex Therapeutics Ltd.
OpenAstexViewer Copyright (C) 2007-2014 Mike Hartshorn





Display Compound Structure Het Het Names Het Formula
60X
60X
(2E,4aR,7aS)-7a-(2,4-difluorophenyl)-6-(5-fluoro-4...
C19 H19 F3 N6 O2
PDB Code5HE7
TitleBACE-1 IN COMPLEX WITH (4AR,7AS)-7A-(2,4-DIFLUOROPHENYL)-6-(5-FLUORO- 4-METHOXY-6-METHYLPYRIMIDIN-2-YL)-2-IMINO-3-METHYLOCTAHYDRO-4H- PYRROLO[3,4-D]PYRIMIDIN-4-ONE
Deposition
Release
Last Modified
ObsoleteNo
ClassificationHYDROLASE/HYDROLASE INHIBITOR
Experiment TypeX-RAY DIFFRACTION
Space GroupP 21 21 21
Resol Range High1.71
Resol Range Low20
Pubmed Id26937601
Doi10.1021/ACS.JMEDCHEM.5B01995
PDB Chain5HE7_A (click to show/hide)
PDB Chain5HE7_B (click to show/hide)