3D Structure Inspector
Structure Overview
Ligand Interactions

5HE5 - Overview - 3D Structure Inspector

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Display Compound Structure Het Het Names Het Formula
TLA
TARTRATE
TLA
L(+)-TARTARIC ACID
C4 H6 O6
60S
60S
5-{(2E,4aR,7aR)-6-[5-fluoro-4-methyl-6-(methylamin...
C18 H19 F N8 O S
PDB Code5HE5
TitleBACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHYL-6-(METHYLAMINO)PYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM
Deposition
Release
Last Modified
ObsoleteNo
ClassificationHYDROLASE/HYDROLASE INHIBITOR
Experiment TypeX-RAY DIFFRACTION
Space GroupP 21 21 21
Resol Range High1.55
Resol Range Low20
Pubmed Id26937601
Doi10.1021/ACS.JMEDCHEM.5B01995
PDB Chain5HE5_B (click to show/hide)
PDB Chain5HE5_A (click to show/hide)