3D Structure Inspector
Structure Overview
Ligand Interactions

5DWR - Overview - 3D Structure Inspector

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Display Compound Structure Het Het Names Het Formula
5H7
5H7
N-{4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridi...
C24 H23 F3 N4 O
SEP
DEXFOSFOSERINE
Dexfosfoserine
GNF-Pf-1028
SEP
PHOSPHOSERINE
C3 H8 N O6 P
PDB Code5DWR
TitleIDENTIFICATION OF N-(4-((1R,3S,5S)-3-AMINO-5-METHYLCYCLOHEXYL)PYRIDIN- 3-YL)-6-(2,6-DIFLUOROPHENYL)-5-FLUOROPICOLINAMIDE (PIM447), A POTENT AND SELECTIVE PROVIRAL INSERTION SITE OF MOLONEY MURINE LEUKEMIA (PIM) 1,2 AND 3 KINASE INHIBITOR IN CLINICAL TRIALS FOR HEMATOLOGICAL MALIGNANCIES
Deposition
Release
Last Modified
ObsoleteNo
ClassificationTRANSFERASE/TRANSFERASE INHIBITOR
Experiment TypeX-RAY DIFFRACTION
Space GroupP 65
Resol Range High2
Resol Range Low42.59
Pubmed Id26505898
Doi10.1021/ACS.JMEDCHEM.5B01275
PDB Chain5DWR_A (click to show/hide)