3D Structure Inspector
Structure Overview
Ligand Interactions

4RWK - Overview - 3D Structure Inspector

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Display Compound Structure Het Het Names Het Formula
MG
/MG
MG
MAGNESIUM ION
Mg
66T
66T
N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-y...
C26 H33 N5 O3
PDB Code4RWK
TitleCRYSTAL STRUCTURE OF V561M FGFR1 GATEKEEPER MUTATION (C488A, C584S, V561M) IN COMPLEX WITH N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H- PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE (AZD4547)
Deposition
Release
Last Modified
ObsoleteNo
ClassificationTRANSFERASE/TRANSFERASE INHIBITOR
Experiment TypeX-RAY DIFFRACTION
Space GroupC 1 2 1
Resol Range High2.98
Resol Range Low50
Pubmed Id25686244
Doi10.1021/ACSCHEMBIO.5B00014
PDB Chain4RWK_B (click to show/hide)
PDB Chain4RWK_A (click to show/hide)