3D Structure Inspector
Structure Overview
Ligand Interactions

4HZT - Overview - 3D Structure Inspector

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Display Compound Structure Het Het Names Het Formula
0ZA
0ZA
3-{(1S)-1-[(6-chloro-3,3-dimethyl-3,4-dihydroisoqu...
C21 H21 Cl N4 O2
ZN
/ZN
ZINC ION
ZN
ZN2
ZINC ION
Zn
PDB Code4HZT
TitleSTRUCTURE-BASED DESIGN OF NOVEL DIHYDROISOQUINOLINE BACE-1 INHIBITORS THAT DO NOT ENGAGE THE CATALYTIC ASPARTATES
Deposition
Release
Last Modified
ObsoleteNo
ClassificationHYDROLASE/HYDROLASE INHIBITOR
Experiment TypeX-RAY DIFFRACTION
Space GroupC 2 2 21
Resol Range High1.8
Resol Range Low60
Pubmed Id23465612
Doi10.1016/J.BMCL.2013.01.103
PDB Chain4HZT_A (click to show/hide)