3D Structure Inspector
Structure Overview
Ligand Interactions

3SKG - Overview - 3D Structure Inspector

Atoms
Solvent
Spheres
Surface
Colour
Opacity
Texture
Background

LeftMouse Rotate
Shift+Left Scale
Ctrl+Left Translate
Click Select
+,− Clipping
r Reset view

AstexViewer™ Copyright (C) 1999-2007 Astex Therapeutics Ltd.
OpenAstexViewer Copyright (C) 2007-2014 Mike Hartshorn





Display Compound Structure Het Het Names Het Formula
PB8
PB8
(2S)-2-[(3R)-3-(acetylamino)-3-(2-methylpropyl)-2-...
C38 H46 F2 N4 O4
PDB Code3SKG
TitleCRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-WT) COMPLEX WITH (2S)-2-((3R)-3-ACETAMIDO-3-ISOBUTYL-2-OXO-1-PYRROLIDINYL)-N- ((1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-(1,2,3,4-TETRAHYDRO-3- ISOQUINOLINYL)ETHYL)-4-PHENYLBUTANAMIDE
Deposition
Release
Last Modified
ObsoleteNo
ClassificationHYDROLASE/HYDROLASE INHIBITOR
Experiment TypeX-RAY DIFFRACTION
Space GroupP 1 21 1
Resol Range High2.878
Resol Range Low30.63
Pubmed Id21974952
Doi10.1016/J.BMCL.2011.06.116
PDB Chain3SKG_D (click to show/hide)
PDB Chain3SKG_B (click to show/hide)
PDB Chain3SKG_E (click to show/hide)
PDB Chain3SKG_A (click to show/hide)