Browse Protein Families
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Browse Protein Families with Family Name Starting with A

0 - 1 - 2 - 3 - 4 - 5 - 6 - 7 - 8 - 9 - A - B - C - D - E - F - G - H - I - J - K - L - M - N - O - P - Q - R - S - T - U - V - W - X - Y - Z - ALL

Family Level # members # members with tested compounds # members with 3D structures # members with Druggable 3D structures
AGC Ser/Thr protein kinase family
family 58 54 39 26
AB hydrolase superfamily
superfamily 51 22 15 10
ABC transporter superfamily
superfamily 49 17 8 8
AAA ATPase family
family 35 6 16 11
actin family
family 28 2 7 4
ATP-dependent AMP-binding enzyme family
family 27 4 2 1
Arf family
family 27 3 11 4
Antp homeobox family
family 26 0 2 0
Adhesion G-protein coupled receptor (ADGR) subfamily
subfamily 25 0 3 1
adenylyl cyclase class-4/guanylyl cyclase family
family 19 17 3 1
acetyltransferase family
family 19 3 10 10
ankyrin SOCS box (ASB) family
family 18 0 2 1
Abd-B homeobox family
family 16 0 4 0
aldehyde dehydrogenase family
family 16 7 9 9
Acetylcholine receptor (TC 1.A.9.1) subfamily
subfamily 16 16 7 3
alpha/beta interferon family
family 16 0 4 3
amino acid/polyamine transporter 2 family
family 16 1 0 0
alpha-carbonic anhydrase family
family 16 13 11 9
aldo/keto reductase family
family 15 7 10 10
amino acid-polyamine-organocation (APC) superfamily
superfamily 15 2 0 0
annexin family
family 14 1 8 6
ATF subfamily
subfamily 13 1 1 0
ABCC family
family 12 11 2 2
ABCA family
family 12 0 0 0
ABCB family
family 11 5 4 4
adaptor complexes large subunit family
family 11 0 6 2
acyl-CoA dehydrogenase family
family 11 0 8 8
ADIPOR family
family 11 0 2 2
anion exchanger (TC 2.A.31) family
family 10 0 1 1
arrestin family
family 10 0 3 1
anoctamin family
family 10 1 0 0
adaptor complexes small subunit family
family 9 0 4 2
Adrenergic receptor subfamily
subfamily 9 9 3 1
amiloride-sensitive sodium channel (TC 1.A.6) family
family 9 6 1 0
adenylate kinase family
family 9 4 7 6
AIG1/Toc34/Toc159-like paraseptin GTPase family
family 8 0 4 2
ATG8 family
family 8 0 6 5
actin-binding proteins ADF family
family 8 1 5 2
A (Shaker) (TC 1.A.1.2) subfamily
subfamily 8 6 3 0
alkB family
family 8 1 5 5
argonaute family
family 8 0 4 2
adaptor complexes medium subunit family
family 8 0 2 2
Alpha-type (group II) subfamily
subfamily 7 0 1 0
apolipoprotein L family
family 7 0 0 0
adenosine and AMP deaminases family
family 6 5 3 1
AhpC/TSA family
family 5 1 5 1
Alpha family
family 5 4 4 4
ABCG family
family 5 1 2 2
ADCK protein kinase family
family 5 2 1 1
ammonium transporter (TC 2.A.49) family
family 5 0 1 0
AP-2 family
family 5 0 0 0
ATPase alpha/beta chains family
family 5 4 0 0
activator 1 small subunits family
family 5 0 0 0
alpha-defensin family
family 5 0 5 1
ANP32 family
family 5 0 3 0
Alpha-type protein kinase family
family 4 1 1 0
Atypical chemokine receptor subfamily
subfamily 4 2 1 0
AB hydrolase 4 family
family 4 0 0 0
ABCD family
family 4 0 0 0
ACDP family
family 4 0 3 1
AF4 family
family 4 0 2 0
AKAP110 family
family 4 0 0 0
ALB/AFP/VDB family
family 4 2 3 2
ATP:guanido phosphotransferase family
family 4 2 4 4
acyl-CoA oxidase family
family 4 0 0 0
aggrecan/versican proteoglycan family
family 4 0 1 0
aldolase class II family
family 4 0 1 0
alkaline phosphatase family
family 4 4 1 0
alpha-actinin family
family 4 0 4 2
apolipoprotein A1/A4/E family
family 4 1 3 1
archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family
family 4 0 1 0
A subfamily
subfamily 4 0 3 0
APG1/unc-51/ULK1 subfamily
subfamily 4 3 2 1
Ago subfamily
subfamily 4 0 2 2
Arg-specific ADP-ribosyltransferase family
family 4 1 0 0
ATR family
family 3 0 2 2
AXUD1 family
family 3 0 0 0
Amer family
family 3 0 1 0
Asx family
family 3 0 0 0
AB hydrolase 2 family
family 3 3 3 1
ABCF family
family 3 0 0 0
ABHD17 family
family 3 1 0 0
ABI family
family 3 0 1 0
ADP-ribosylglycohydrolase family
family 3 0 2 1
AKAP95 family
family 3 0 0 0
AMIGO family
family 3 0 0 0
ANKRD34 family
family 3 0 0 0
ANKRD36 family
family 3 0 0 0
APP family
family 3 1 3 2
ASPP family
family 3 0 2 0
ATP-dependent DNA ligase family
family 3 1 3 2
ATPase C chain family
family 3 0 3 0
acid sphingomyelinase family
family 3 1 2 1
aconitase/IPM isomerase family
family 3 0 1 1
adenosylhomocysteinase family
family 3 1 3 3
adrenomedullin family
family 3 2 1 0
alkaline ceramidase family
family 3 1 0 0
alpha-ketoglutarate dehydrogenase family
family 3 1 1 0
amidase family
family 3 2 0 0
angiomotin family
family 3 0 0 0
archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family
family 3 0 1 0
arginase family
family 3 2 2 2
aspartyl/asparaginyl beta-hydroxylase family
family 3 0 1 0
ALPK subfamily
subfamily 3 0 0 0
AQP11/AQP12 subfamily
subfamily 3 0 0 0
ARD1 subfamily
subfamily 3 0 0 0
ATP-dependent PFK group I subfamily
subfamily 3 1 2 2
AXL/UFO subfamily
subfamily 3 3 3 1
Adducin subfamily
subfamily 3 0 0 0
Aldo/keto reductase 2 subfamily
subfamily 3 0 2 2
Aurora subfamily
subfamily 3 3 2 2
ATXN1 family
family 2 0 1 1
Aspartoacylase subfamily
subfamily 2 0 1 1
AVIT (prokineticin) family
family 2 0 0 0
AccD/PCCB family
family 2 0 0 0
AdoMet synthase family
family 2 0 2 0
Arkadia family
family 2 0 2 0
AspA/AstE family
family 2 0 1 1
ABHD14 family
family 2 0 1 0
ABHD16 family
family 2 1 0 0
ADAD family
family 2 0 0 0
ADP-ribosyl cyclase family
family 2 1 2 2
AGR family
family 2 0 2 1
AHA1 family
family 2 0 1 0
AIG1 family
family 2 0 0 0
ALG10 glucosyltransferase family
family 2 0 0 0
ALG6/ALG8 glucosyltransferase family
family 2 0 0 0
APH-1 family
family 2 2 1 1
ARMET family
family 2 0 2 0
ARPC5 family
family 2 0 0 0
ASF1 family
family 2 0 2 0
ATG2 family
family 2 0 0 0
ATG9 family
family 2 0 0 0
ATP synthase subunit s family
family 2 0 0 0
ATPase g subunit family
family 2 0 0 0
acid ceramidase family
family 2 2 0 0
acylphosphatase family
family 2 0 1 1
adenomatous polyposis coli (APC) family
family 2 0 1 1
adenylosuccinate synthetase family
family 2 1 1 1
adipolin/erythroferrone family
family 2 0 0 0
adrenodoxin/putidaredoxin family
family 2 0 2 1
akirin family
family 2 0 0 0
amelogenin family
family 2 0 0 0
apolipoprotein O/MICOS complex subunit Mic27 family
family 2 0 0 0
archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family
family 2 0 1 1
arylamine N-acetyltransferase family
family 2 2 2 2
astrotactin family
family 2 0 1 0
ataxin-2 family
family 2 0 1 0
ABHD4/ABHD5 subfamily
subfamily 2 0 0 0
ABL subfamily
subfamily 2 2 2 2
AFG2 subfamily
subfamily 2 1 0 0
AK3 subfamily
subfamily 2 1 2 2
AKR/ZDHHC17 subfamily
subfamily 2 0 1 0
ARP1 subfamily
subfamily 2 0 0 0
ARP3 subfamily
subfamily 2 0 1 1
ATM subfamily
subfamily 2 2 0 0
Alanine aminotransferase subfamily
subfamily 2 1 1 0
Ariadne subfamily
subfamily 2 0 1 1
AUTS2 family
family 2 0 0 0
anaerobic coproporphyrinogen-III oxidase family
family 1 0 0 0
anamorsin family
family 1 0 1 1
apelin family
family 1 1 0 0
apolipoprotein A2 family
family 1 0 1 0
apolipoprotein C1 family
family 1 0 1 0
apolipoprotein C2 family
family 1 0 1 0
apolipoprotein C3 family
family 1 0 1 0
apolipoprotein C4 family
family 1 0 0 0
apyrase family
family 1 0 1 1
archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family
family 1 0 1 1
archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family
family 1 0 1 0
archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family
family 1 0 1 0
archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family
family 1 0 1 0
archease family
family 1 0 0 0
argininosuccinate synthase family
family 1 0 1 1
aromatic-ring hydroxylase family
family 1 1 0 0
arsA ATPase family
family 1 0 0 0
ashwin family
family 1 0 0 0
asteroid family
family 1 0 0 0
asunder family
family 1 0 0 0
ataxin-10 family
family 1 0 0 0
ataxin-7 family
family 1 0 1 0
augurin family
family 1 0 0 0
AANAT subfamily
subfamily 1 0 0 0
ADAT2 subfamily
subfamily 1 0 1 0
ADAT3 subfamily
subfamily 1 0 0 0
ADGF subfamily
subfamily 1 0 1 1
AK1 subfamily
subfamily 1 1 1 1
AK2 subfamily
subfamily 1 1 1 1
AK6 subfamily
subfamily 1 0 1 1
AMPK subfamily
subfamily 1 1 0 0
ARP2 subfamily
subfamily 1 1 1 1
ARP5 subfamily
subfamily 1 0 0 0
ARP6 subfamily
subfamily 1 0 0 0
ARP8 subfamily
subfamily 1 0 1 0
ASIC1 subfamily
subfamily 1 1 0 0
ASIC2 subfamily
subfamily 1 1 0 0
ASIC3 subfamily
subfamily 1 1 0 0
ASIC4 subfamily
subfamily 1 0 0 0
ASIC5 subfamily
subfamily 1 0 0 0
ATP-specific subunit beta subfamily
subfamily 1 0 0 0
Abraxas subfamily
subfamily 1 0 1 0
Abro1 subfamily
subfamily 1 0 0 0
Adenylosuccinate lyase subfamily
subfamily 1 0 1 1
Agmatinase subfamily
subfamily 1 0 0 0
Alax-L subfamily
subfamily 1 0 0 0
ArgK/MeaB subfamily
subfamily 1 0 1 1
Argininosuccinate lyase subfamily
subfamily 1 0 1 1
APC15 family
family 1 0 1 0
APC16 family
family 1 0 1 0
APC3/CDC27 family
family 1 0 1 1
APC4 family
family 1 0 1 1
APC5 family
family 1 0 1 1
APC6/CDC16 family
family 1 0 1 1
APC7 family
family 1 0 1 1
APC8/CDC23 family
family 1 0 1 1
APCDD1 family
family 1 0 0 0
API5 family
family 1 0 1 0
APLF family
family 1 0 1 1
APOPT family
family 1 0 0 0
ARC/ARG3.1 family
family 1 0 0 0
ARID5B family
family 1 0 1 0
ARL2BP family
family 1 0 1 1
ARL6IP4 family
family 1 0 0 0
ARL6IP6 family
family 1 0 0 0
ARL6ip family
family 1 0 0 0
ARMC6 family
family 1 0 0 0
ARMT1 family
family 1 0 0 0
AROS family
family 1 0 0 0
ARPC2 family
family 1 0 0 0
ARPC3 family
family 1 0 1 1
ARPC4 family
family 1 0 1 0
ARS2 family
family 1 0 0 0
ARV1 family
family 1 0 0 0
ASCC2 family
family 1 0 1 0
ATCase/OTCase family
family 1 1 1 1
ATG10 family
family 1 0 0 0
ATG101 family
family 1 0 1 1
ATG12 family
family 1 0 1 0
ATG13 family
family 1 0 1 0
ATG14 family
family 1 0 0 0
ATG17 family
family 1 0 0 0
ATG3 family
family 1 0 1 0
ATG37 family
family 1 0 1 1
ATG5 family
family 1 0 1 1
ATG7 family
family 1 1 0 0
ATP11 family
family 1 0 0 0
ATP12 family
family 1 0 0 0
ATPase A chain family
family 1 0 0 0
ATPase F chain family
family 1 0 0 0
ATPase d subunit family
family 1 0 0 0
ATPase delta chain family
family 1 0 0 0
ATPase e subunit family
family 1 0 0 0
ATPase epsilon chain family
family 1 0 0 0
ATPase gamma chain family
family 1 0 0 0
ATPase inhibitor family
family 1 0 0 0
acetyltransferase ATAT1 family
family 1 0 1 1
acireductone dioxygenase (ARD) family
family 1 0 1 0
activator 1 large subunit family
family 1 0 1 0
acyl carrier protein (ACP) family
family 1 0 1 0
acyl coenzyme A hydrolase family
family 1 0 0 0
adipogenin family
family 1 0 0 0
aerobic coproporphyrinogen-III oxidase family
family 1 1 1 1
aldose epimerase family
family 1 0 1 1
allantoicase family
family 1 0 0 0
alpha-2-MRAP family
family 1 0 1 0
alpha-casein family
family 1 0 0 0
ameloblastin family
family 1 0 0 0
amelotin family
family 1 0 0 0
amidinotransferase family
family 1 0 1 1
aminoglycoside phosphotransferase family
family 1 0 0 0
amphiregulin family
family 1 1 1 0
ADRB3 sub-subfamily
subsubfamily 1 1 0 0
Alpha-10/CHRNA10 sub-subfamily
subsubfamily 1 1 0 0
Alpha-7/CHRNA7 sub-subfamily
subsubfamily 1 1 1 1
ADRA2C sub-subfamily
subsubfamily 1 1 0 0
Alpha-9/CHRNA9 sub-subfamily
subsubfamily 1 1 1 1
ADRA1B sub-subfamily
subsubfamily 1 1 0 0
ADRA1A sub-subfamily
subsubfamily 1 1 0 0
Alpha-1/CHRNA1 sub-subfamily
subsubfamily 1 1 1 0
Alpha-3/CHRNA3 sub-subfamily
subsubfamily 1 1 1 0
Alpha-2/CHRNA2 sub-subfamily
subsubfamily 1 1 1 0
Alpha-6/CHRNA6 sub-subfamily
subsubfamily 1 1 0 0
Alpha-4/CHRNA4 sub-subfamily
subsubfamily 1 1 1 0
Alpha-5/CHRNA5 sub-subfamily
subsubfamily 1 1 0 0
ADRA2A sub-subfamily
subsubfamily 1 1 1 0
ADRB1 sub-subfamily
subsubfamily 1 1 1 0
ADRA2B sub-subfamily
subsubfamily 1 1 0 0
A-like 1 sub-subfamily
subsubfamily 1 0 0 0
ADRB2 sub-subfamily
subsubfamily 1 1 1 1
ADRA1D sub-subfamily
subsubfamily 1 1 0 0
A-like 2 sub-subfamily
subsubfamily 1 0 0 0
ATPase protein 8 family
family 1 0 0 0
ATRIP family
family 1 0 1 0
ATX1 family
family 1 0 1 1
ATZ/TRZ family
family 1 1 1 1
AUP1 family
family 1 0 1 0
AVL9 family
family 1 0 0 0
AcpS family
family 1 1 1 1
Arpin family
family 1 0 1 0
Asterix family
family 1 0 0 0
AAED1 family
family 1 0 0 0
AAMDC family
family 1 0 1 0
AAR2 family
family 1 0 0 0
AATF family
family 1 0 0 0
ABCE family
family 1 0 0 0
ABP1 family
family 1 0 1 0
ACBD7 family
family 1 0 1 0
ACBP family
family 1 0 1 0
ACMSD family
family 1 0 1 1
ADAT1 family
family 1 0 0 0
ADIP family
family 1 0 0 0
ADP-dependent glucokinase family
family 1 0 0 0
ADPRibase-Mn family
family 1 0 0 0
ADRM1 family
family 1 0 1 1
AEBP2/jing C2H2-type zinc-finger family
family 1 1 0 0
AFG1 ATPase family
family 1 0 0 0
AHSP family
family 1 0 1 0
AIDA family
family 1 0 0 0
AKNA family
family 1 0 0 0
ALAD family
family 1 1 1 1
ALEX family
family 1 0 0 0
ALG14 family
family 1 0 0 0
ALYREF family
family 1 0 1 1
AMN1 family
family 1 0 0 0
AMY1 family
family 1 0 1 0
ANF homeobox family
family 1 0 1 0
ANF receptor family
family 1 1 1 1
ANGPTL8 family
family 1 0 0 0
ANKH family
family 1 0 0 0
ANKLE2 family
family 1 0 0 0
ANKRD39 family
family 1 0 0 0
ANKZF1/VMS1 family
family 1 0 0 0
APC1 family
family 1 0 1 1
APC10 family
family 1 0 1 0
APC13 family
family 1 0 1 0