Protein Family Synopsis
Family Overview
Special Analysis

Type IIA subfamily - Overview - Protein Family Synopsis

THE COMPLEX OF WILD-TYPE B-RAF WITH PYRAZOLO PYRIMIDINE INHIBITOR (PDB: 3II5)

Members
(human, all organisms)
5, 45
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
2, 5
Members with tested compounds
(human, all organisms)
2, 3
Members with active compounds (<100nM)
(human, all organisms)
1, 2
Members with mutations reported
(human, all organisms)
5, 5

Lineage


cation transport ATPase (P-type) (TC 3.A.3) family (36)
+ Unclassified (5)
ATP13A1
ATP13A2
ATP13A3
ATP13A4
ATP13A5
+ Type IB subfamily (2)
ATP7A
ATP7B
+ Type IIA subfamily (5) *
ATP2A1
ATP2A2
ATP2A3
ATP2C1
ATP2C2
+ Type IIB subfamily (4)
ATP2B1
ATP2B2
ATP2B3
ATP2B4
+ Type IIC subfamily (6)
ATP12A
ATP1A1
ATP1A2
ATP1A3
ATP1A4
ATP4A
+ Type IV subfamily (14)
ATP10A
ATP10B
ATP10D
ATP11A
ATP11B
ATP11C
ATP8A1
ATP8A2
ATP8B1
ATP8B2
ATP8B3
ATP8B4
ATP9A
ATP9B
+ Type V subfamily (5)
ATP13A1
ATP13A2
ATP13A3
ATP13A4
ATP13A5