Protein Family Synopsis
Family Overview
Special Analysis

TrmB family - Overview - Protein Family Synopsis

THE COMPLEX OF WILD-TYPE B-RAF WITH PYRAZOLO PYRIMIDINE INHIBITOR (PDB: 3II5)

Members
(human, all organisms)
1, 551
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
1, 5
Members with tested compounds
(human, all organisms)
0, 0
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
1, 1

Lineage


class I-like SAM-binding methyltransferase superfamily (63)
BUD23/WBSCR22 family (1)
+ Unclassified (1)
BUD23
C5-methyltransferase family (4)
+ Unclassified (4)
TRDMT1
DNMT1
DNMT3B
DNMT3A
CLNMT methyltransferase family (1)
+ Unclassified (1)
CAMKMT
Cation-dependent O-methyltransferase family (3)
+ Unclassified (3)
COMT
COMTD1
LRTOMT
Cation-independent O-methyltransferase family (2)
+ Unclassified (2)
ASMTL
ASMT
DOT1 family (1)
+ Unclassified (1)
DOT1L
EEF2KMT family (5)
+ Unclassified (5)
FAM86C2P
FAM86B2
FAM86B1
EEF2KMT
FAM86C1
EFM4 family (1)
+ Unclassified (1)
EEF1AKMT2
EFM5 family (1)
+ Unclassified (1)
EEF1AKMT1
Glycine N-methyltransferase family (1)
+ Unclassified (1)
GNMT
HNMT family (1)
+ Unclassified (1)
HNMT
MenG/UbiE family (1)
+ Unclassified (1)
COQ5
NNMT/PNMT/TEMT family (3)
+ Unclassified (3)
INMT
PNMT
NNMT
Protein arginine N-methyltransferase family (9)
+ Unclassified (6)
PRMT5
PRMT3
PRMT2
PRMT9
CARM1
PRMT1
+ PRMT6 subfamily (1)
PRMT6
+ PRMT7 subfamily (1)
PRMT7
+ PRMT8 subfamily (1)
PRMT8
RMT2 methyltransferase family (1)
+ Unclassified (1)
GAMT
RNA M5U methyltransferase family (2)
+ Unclassified (2)
TRMT2A
TRMT2B
RNA methyltransferase RlmE family (3)
+ Unclassified (1)
MRM2
+ SPB1 subfamily (1)
FTSJ3
+ TRM7 subfamily (1)
FTSJ1
RsmB/NOP family (9)
+ Unclassified (8)
NOP2
NSUN5P1
NSUN5P2
NSUN7
NSUN6
NSUN4
NSUN5
NSUN3
+ TRM4 subfamily (1)
NSUN2
TPMT family (1)
+ Unclassified (1)
TPMT
TRM11 methyltransferase family (1)
+ Unclassified (1)
TRMT11
TRM5/TYW2 family (2)
+ Unclassified (2)
TRMT5
TRMT12
TRM61 family (2)
+ Unclassified (2)
TRMT61A
TRMT61B
Trm1 family (2)
+ Unclassified (2)
TRMT1L
TRMT1
TrmB family (1) *
+ Unclassified (1)
METTL1
UbiG/COQ3 family (1)
+ Unclassified (1)
COQ3
mRNA cap 0 methyltransferase family (1)
+ Unclassified (1)
RNMT
rRNA adenine N(6)-methyltransferase family (3)
+ Unclassified (1)
DIMT1
+ KsgA subfamily (2)
TFB1M
TFB2M