Protein Family Synopsis
Family Overview
Special Analysis

Kv7.4/KCNQ4 sub-subfamily - Overview - Protein Family Synopsis

THE COMPLEX OF WILD-TYPE B-RAF WITH PYRAZOLO PYRIMIDINE INHIBITOR (PDB: 3II5)

Members
(human, all organisms)
1, 3
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
1, 1
Members with tested compounds
(human, all organisms)
1, 1
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
1, 1

Lineage


potassium channel family (44)
+ A (Shaker) (TC 1.A.1.2) subfamily (8)
+ Kv1.1/KCNA1 sub-subfamily (1)
KCNA1
+ Kv1.2/KCNA2 sub-subfamily (1)
KCNA2
+ Kv1.3/KCNA3 sub-subfamily (1)
KCNA3
+ Kv1.4/KCNA4 sub-subfamily (1)
KCNA4
+ Kv1.5/KCNA5 sub-subfamily (1)
KCNA5
+ Kv1.6/KCNA6 sub-subfamily (1)
KCNA6
+ Kv1.7/KCNA7 sub-subfamily (1)
KCNA7
+ Kv1.8/KCNA10 sub-subfamily (1)
KCNA10
+ B (Shab) (TC 1.A.1.2) subfamily (2)
+ Kv2.1/KCNB1 sub-subfamily (1)
KCNB1
+ Kv2.2/KCNB2 sub-subfamily (1)
KCNB2
+ C (Shaw) (TC 1.A.1.2) subfamily (4)
+ Kv3.1/KCNC1 sub-subfamily (1)
KCNC1
+ Kv3.2/KCNC2 sub-subfamily (1)
KCNC2
+ Kv3.3/KCNC3 sub-subfamily (1)
KCNC3
+ Kv3.4/KCNC4 sub-subfamily (1)
KCNC4
+ Calcium-activated (TC 1.A.1.3) subfamily (4)
+ KCa1.1/KCNMA1 sub-subfamily (1)
KCNMA1
+ KCa4.1/KCNT1 sub-subfamily (1)
KCNT1
+ KCa4.2/KCNT2 sub-subfamily (1)
KCNT2
+ KCa5.1/KCNU1 sub-subfamily (1)
KCNU1
+ D (Shal) (TC 1.A.1.2) subfamily (3)
+ Kv4.1/KCND1 sub-subfamily (1)
KCND1
+ Kv4.2/KCND2 sub-subfamily (1)
KCND2
+ Kv4.3/KCND3 sub-subfamily (1)
KCND3
+ F (TC 1.A.1.2) subfamily (1)
+ Kv5.1/KCNF1 sub-subfamily (1)
KCNF1
+ G (TC 1.A.1.2) subfamily (4)
+ Kv6.1/KCNG1 sub-subfamily (1)
KCNG1
+ Kv6.2/KCNG2 sub-subfamily (1)
KCNG2
+ Kv6.3/KCNG3 sub-subfamily (1)
KCNG3
+ Kv6.4/KCNG4 sub-subfamily (1)
KCNG4
+ H (Eag) (TC 1.A.1.20) subfamily (8)
+ Kv10.1/KCNH1 sub-subfamily (1)
KCNH1
+ Kv10.2/KCNH5 sub-subfamily (1)
KCNH5
+ Kv11.1/KCNH2 sub-subfamily (1)
KCNH2
+ Kv11.2/KCNH6 sub-subfamily (1)
KCNH6
+ Kv11.3/KCNH7 sub-subfamily (1)
KCNH7
+ Kv12.1/KCNH8 sub-subfamily (1)
KCNH8
+ Kv12.2/KCNH3 sub-subfamily (1)
KCNH3
+ Kv12.3/KCNH4 sub-subfamily (1)
KCNH4
+ KQT (TC 1.A.1.15) subfamily (5)
+ Kv7.1/KCNQ1 sub-subfamily (1)
KCNQ1
+ Kv7.2/KCNQ2 sub-subfamily (1)
KCNQ2
+ Kv7.3/KCNQ3 sub-subfamily (1)
KCNQ3
+ Kv7.4/KCNQ4 sub-subfamily (1) *
KCNQ4
+ Kv7.5/KCNQ5 sub-subfamily (1)
KCNQ5
+ S (TC 1.A.1.2) subfamily (3)
+ Kv9.1/KCNS1 sub-subfamily (1)
KCNS1
+ Kv9.2/KCNS2 sub-subfamily (1)
KCNS2
+ Kv9.3/KCNS3 sub-subfamily (1)
KCNS3
+ V (TC 1.A.1.2) subfamily (2)
+ Kv8.1/KCNV1 sub-subfamily (1)
KCNV1
+ Kv8.2/KCNV2 sub-subfamily (1)
KCNV2