Protein Family Synopsis
Family Overview
Special Analysis

K-HECT subfamily - Overview - Protein Family Synopsis

THE COMPLEX OF WILD-TYPE B-RAF WITH PYRAZOLO PYRIMIDINE INHIBITOR (PDB: 3II5)

Members
(human, all organisms)
2, 13
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
1, 1
Members with tested compounds
(human, all organisms)
0, 0
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
2, 2

Lineage


UPL family (3)
+ Unclassified (1)
HUWE1
+ K-HECT subfamily (2) *
HECTD1
TRIP12
+ TOM1/PTR1 subfamily (1)
HUWE1